For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...
Microtubules, the dynamic filaments that form the cell's internal scaffolding, have long been viewed as mere passive structural supports. But a new study reveals they play a far more active signaling ...
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally ...
In each cell of your body, DNA is stored in structures called chromosomes. When cells divide, these chromosomes are copied, ...
A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in keeping cells healthy. Using yeast, the researchers ...
Cells that acquire a doubled genome after a failed division step survive and proliferate far more effectively than cells left ...
As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...
Structure of Ndc80 complex bound to microtubule. Ndc80 complex is the major microtubule3binding module at the kinetochore. Green: α-tubulin, light-blue:β-tubulin, dark blue: HEC1 (a4subunit of the ...