Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

eDL-cSIM: An AI-driven super-resolution imaging method that captures high-quality live-cell dynamics in a single exposure, enhancing speed, resolution, and environmental robustness for advanced ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Super-resolution microscopy has transformed the study of renal podocytes by breaking through the ~250 nm diffraction limit of conventional light microscopy. Podocytes, with their interdigitating foot ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

Super-resolution fluorescence microscopy has transformed our ability to visualise biological structures at the nanoscale by breaking the classical diffraction barrier of light. Traditional optical ...

There is a growing demand for non-invasive insights into the complex three-dimensional subcellular dynamics within living tissues on the frontier of biological research. To achieve simultaneous ...

Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

A new microscopy approach revealed that the glycocalyx, a sugar coating surrounding cells, changes its molecular arrangement ...

Christophe Leterrier uses advanced microscopy to uncover neurons’ intricate nanostructure and dynamics while creating ...

MINFLUX is a super-resolution microscopy protocol designed to improve the localizing of specific photon emitters in space. Developed in 2016 by a German team including super-resolution pioneer and ...