Toll-like receptors (TLRs) constitute a critical family of proteins that detect conserved microbial structures, known as pathogen-associated molecular patterns (PAMPs), to rapidly initiate the innate ...

Toll-like receptor (TLR) and saponin adjuvants have each improved vaccine potency and safety. Now, researchers at Stanford University report that combining them in a nanoparticle format improves not ...

Toll-like receptors (TLRs) are crucial to trigger anticancer immune responses. Despite the promise of TLR agonists as potential anticancer agents, few have reached the clinics due to concerns related ...

An oral therapy targeting toll-like receptors (TLR) 7 and 8 reduced disease activity in patients with cutaneous lupus erythematosus (CLE) or systemic lupus erythematosus (SLE) with active lupus rash.

BURLINGAME, Calif.--(BUSINESS WIRE)--Tallac Therapeutics, Inc., a privately held biopharmaceutical company harnessing the power of innate and adaptive immunity to fight cancer, today announced the U.S ...

"Toll-Like Receptor 8 (TLR8) Agonist Clinical Trials"DelveInsight's,“Toll-Like Receptor 8 Agonist - Pipeline Insight, 2025” report provides comprehensive insights about 8+ companies and 10+ pipeline ...

Filoviruses are negative-sense and single-stranded ribonucleic acid (RNA) viruses. The most well-known human-infecting filoviruses are marburgviruses and ebolaviruses. Infection can result in ...