Background and Aim: Although increased mast cells in the gut and their role in visceral hypersensitivity in irritable bowel syndrome have been postulated, this relationship remains unclear. Our aim ...

The current treatment of irritable bowel syndrome (IBS) is still problematic. Several agents that were introduced in the past had side effects that led to their removal from the market. Klooker and ...

Irritable bowel syndrome patients extensively suffer from chronic visceral hypersensitivity, with involvement of all levels of the brain-gut axis, as well as various neurotransmitters. Chronic ...

Please provide your email address to receive an email when new articles are posted on . Ebastine, a histamine receptor H1 antagonist, was found to reduce visceral hypersensitivity, symptoms and ...

Gastroesophageal reflux disease (GERD) isn’t just about esophageal acid exposure anymore. Researchers in Korea published a review of data on GERD and the different ways it presents among men and women ...