Confirmed team news, predicted lineup and injury latest for Premier League - Ruben Amorim could make changes as a busy schedule continues

Follow live coverage as Manchester United face Southampton today in the Premier League. Another top-flight season will be covered in full right here with The Independent, as reigning champions Manchester City look to make it an unprecedented five titles in a row come the end of 2024/25.

Amad's first professional hat-trick spared United's blushes at Old Trafford as they came back to beat Southampton

Two sides looking to push on from confidence-building wins in the FA Cup meet at Old Trafford on Thursday as Man United host Southampton in the English Premier League. United boss Ruben Amorim will have been delighted by his side's resilience after edging past Arsenal on penalties on Sunday,

This evening’s match presents the perfect chance to make a positive start, as they face a Southampton side who sit bottom of the table with just six points so far this season. The Saints’ struggles have continued even since the arrival of new manager Ivan Juric,

Manchester United hope to win their first Premier League match in a month when they host last-place Southampton.