Different pathways within the cell are activated or silenced dependent on the external signals acting on a cell. One such pathway includes the stimulator of interferon genes (STING) pathway which acts ...

There is significant crosstalk between DNA damage response (DDR) pathways and innate immune pathways. Both the individual pathways and their interactions are key areas of interest for the development ...

Monocytes, a special type of white blood cell, play an important role in the innate immune system and contribute to host defense in the blood by secreting large quantities of pro-inflammatory ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital published today in ...

Clarivate plc has unveiled the 2025 Citation Laureates. Widely considered a predictor of the Nobel Prizes, this recognition has highlighted the discovery of biomolecular condensates in chemistry and ...

Scientists generally agree that eukaryotes, the domain of life whose cells contain nuclei and that includes almost all multicellular organisms, originated from a process involving the symbiotic union ...

The VDR is a member of the steroid/hormone nuclear receptor superfamily that includes 48 ligand-activated transcription factors. [3] These factors bind to conserved elements in the promoters of genes ...

FRANKFURT. It is extremely dangerous when, in response to either viral intruders or damage within the cell itself, DNA appears in the cytoplasm of a cell. Our immune system is then called upon to ...

Researchers have observed rapid and distinct immune system changes in a small study of people who switched to a vegan or a ketogenic (also called keto) diet. Scientists closely monitored various ...