Primary lateral sclerosis (PLS) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases. PLS typically develops slowly, while ALS rapidly affects mobility and can become fatal.

When you take a walk, talk to a friend, or chew a piece of food, motor neurons are behind these movements. Just like other parts of your body, they can become damaged. You may have heard of ALS, ...

Primary lateral sclerosis (PLS) is a rare neurological disorder that affects the motor neurons in the brain and spinal cord, which control movement. It is a form of motor neuron disease (MND). PLS ...

Hereditary spastic paraplegia (HSP), also known as familial spastic paraparesis, is a term used for a group of inherited diseases that affect the upper motor neurons traveling from the brain through ...

A diagnosis of amyotrophic lateral sclerosis can be overlooked by clinicians unfamiliar with the various signs of the disease. ALS is purely a motor neuron disease; sensory neurons are not affected. 4 ...

Primary lateral sclerosis (PLS) is a motor neuron disease variation of ALS (amyotrophic lateral sclerosis) but far more rare. PLS refers to patients who seem to have disruptions with only upper motor ...

Amyotrophic lateral sclerosis (ALS) is a devastating, fatal neuromuscular disease. Most patients die within 2 to 5 years of diagnosis. The disease stems from death of upper and lower motor neurons ...

BUFFALO, N.Y. — Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks. This miniature highway system is vital for keeping ...

Dr. Amanda C. Guidon: A 60-year-old man was evaluated in the neurology clinic of this hospital because of weakness and difficulty chewing. Six months before this presentation, weakness developed in ...

A drug candidate found to protect nerve cells damaged by motor neuron disease (MND), could offer new hope to people living ...