Formal adoption of PMOS replaces a cyst-centric label with terminology capturing endocrine, metabolic, and ovarian dysfunction that drives infertility, menstrual irregularity, and long-term ...

Accelerated approval covers post–BTK inhibitor relapsed/refractory MCL, making sonrotoclax the only BCL2 inhibitor specifically approved for this indication. Independent Lugano-assessed efficacy in ...

Regulatory clearance creates an at-home, 28-day cycle option using oral decitabine/cedazuridine on days 1–5 plus venetoclax 400 mg daily after a ramp-up cycle. Efficacy signals in ASCERTAIN-V included ...

An international consortium of pediatric oncology experts has published consensus guidelines on radiation treatment for children with metastatic rhabdomyosarcoma (RMS), offering site-specific ...

Food insecurity identification modeling for Medicare can establish a reliable method of prioritizing members at risk of food ...

RBM20 truncating variants ( RBM20 tvs) appear to contribute to arrhythmogenic dilated cardiomyopathy (DCM) but with ...

Single adequate and well-controlled trial plus confirmatory evidence became the default approval paradigm, formalizing a trend already common for first-in-class oncology and rare-disease products.

In part 2 of her interview with The American Journal of Managed Care®, Deborah Doroshow, MD, PhD, assistant professor of ...

Women with endometriosis have an elevated risk of developing epithelial ovarian cancer, but, when they do develop it, they ...

Scott Shannon, MD, discusses psychedelic therapies, federal policy shifts, and the barriers slowing mental health innovation.

Private equity (PE) has played a large and growing role in shaping the American health care landscape. Over the past decade ...

Placebo-controlled evidence across 9013 patients showed a lower composite risk (HR 0.85) driven by reduced worsening HF ...