The Cleveland Browns and San Francisco 49ers kicked off their practice week on Wednesday with Thanksgiving just a sleep away.

See who's in and who's out for the Week 13 matchup between the San Francisco 49ers and Cleveland Browns on November 30, 2025.

ESPN's Jeremy Fowler provided a reason for the San Francisco 49ers waiving the guarantees on Brandon Aiyuk's contract.

The San Francisco 49ers will deal with many of the same injury issues they dealt with in Week 12, with a couple exceptions.

The 49ers' injury report highlights five who miss practice as the team prepares for its Week 13 matchup against the Browns in ...

On Sunday, Kyle Shanahan will be tasked with leading the San Francisco 49ers past the new Cleveland Browns starting ...

ESPN NFL insider Jeremy Fowler provided an interesting update on Aiyuk's future in San Francisco. While he reports this saga ...

It appears the 49ers and their oft-injured WR are headed for a divorce after the team voided $27 million in 2026 salary guarantees ...

The Las Vegas Raiders fired offensive coordinator Chip Kelly following Sunday's loss to the Cleveland Browns, and things were ...

The Seattle Seahawks are being linked to a star playmaker amid the expected "stunning split" between the San Francisco 49ers ...

Kyle Shanahan addresses facing the son of his boyhood hero Deion Sanders and what makes Myles Garrett so great.

Mary Kay Cabot, Ashley Bastock and Dan Labbe talk Shedeur Sanders' second start, chemistry with Jerry Jeudy and Myles Garrett ...