Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

Scientists have visualized for the first time how opioids such as loperamide and the antidote naloxone engage a key brain receptor, offering insight that could lead to better pain treatments.

The group of researchers were the first to take snapshots of the moment naloxone reverses an opioid overdose in the brain.

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid receptors. What they didn't know—until now—was exactly what happens next. A ...

While the FDA has classified synthetic kratom as a public health threat and dozens of states have enacted regulations or bans ...

A proposal to ban the sale of a powerful synthetic compound derived from the kratom plant advanced at Rockford City Council ...

Listening to a favorite song can trigger a profound emotional response that rivals the feelings produced by biological ...

Yichang Humanwell Pharmaceutical Co. Ltd. has disclosed morphinan derivatives acting as κ-opioid receptor agonists reported to be useful for the treatment of pain and pruritus.

Gov. Andy Beshear announced his administration is taking action to prevent the sale and distribution of a dangerous substance ...