Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

The group of researchers were the first to take snapshots of the moment naloxone reverses an opioid overdose in the brain.

Discover the profound impact of opioids on your brain. In this eye-opening video, neuropharmacologist Lauren Purington delves into the intricate effects of opioids on the human brain and body. From ...

Opioid agonists are substances that activate opioid receptors in the central and peripheral nervous systems. They have several uses, from pain management to treating opioid use disorder. You have ...

Opioids are commonly known as powerful painkillers with strong psychoactive effects. They increase dopamine signaling in the brain, producing pleasurable sensations that can encourage repeated use and ...

Kappa-opioid receptor (KOR) agonists represent a promising class of compounds that modulate pain, mood and various neurobehavioural processes. Unlike traditional opioids that primarily target the ...

America remains in the grips of an opioid epidemic. Over the past 25 years or so, opioid overdose deaths have been rising steadily, reaching a record 81,806 in 2022, and not budging much since. Drugs ...

Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose.