Alzheimer's disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that ...

This study presents valuable findings on the patterned loss of Purkinje cells in the mouse cerebellum during aging. Convincing evidence shows that Purkinje cell loss with aging occurs in a pattern of ...

This study presents a fundamental discovery of how cerebellar climbing fibers modulate plastic changes in the somatosensory cortex by identifying both the responsible cortical circuit and the ...

Abstract: Functional connectivity between the cerebellum and the motor cortex is critical for motor function. Low-intensity transcranial ultrasound stimulation (TUS) has been proved to directly ...

WEDNESDAY, Aug. 6, 2025 (HealthDay News) -- For patients with early Parkinson disease (PD), regular physical activity is associated with a slower rate of neurodegeneration, according to a study ...

Cerebellar ataxia results from dysfunction of the cerebellum, which is part of the brain that helps regulate and control movement and balance. People may experience changes in gait, speech, and eye ...

Brain imaging in MSA revealed that distinct cerebellar and medullary atrophy patterns were closely linked to cardiovascular autonomic dysfunction. A study published in June 2025 issue of European ...

Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are sporadic four-repeat tauopathies that have characteristic clinical and neuropathologic profiles, but also share overlapping ...

Fear is a fundamental emotion necessary for survival. We experience fear in several ways that have helped humans stay alive, but it can go beyond what is appropriate for survival. Persistent fear and ...

1 Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan 2 Department of Biological Sciences, Columbia University in the City of New York, New York, NY, United States The cerebellum plays ...