Surgical resection remains the cornerstone of management for chondrosarcoma and chordoma. However, the application of new biologic insights to therapeutic development indicates that improved ...

Regorafenib (Stivarga) did not improve progression-free survival in patients with advanced or metastatic chordoma, according to the noncomparative phase II REGOBONE study, which was presented at the ...

Sacrococcygeal chordoma is rare, with a risk of local relapse of 50%, and metastasis relapse estimated at 17.5% in all cases. 1 Only one metastatic case to the penis has been reported. 2 We report the ...

Study showed signs of clinical activity, but failed to meet the primary endpoint of the Phase 2 study Two ongoing phase 1 trials are exploring the intravenous administration of two different MVA-based ...

During his freshman year at Duke University, a persistent headache sent Josh Sommer on a diagnostic journey. The reveal: a tumor right below his pituitary gland in front of his brainstem. Called a ...

A new study adds to a growing body of evidence that organoids -- lab-grown collections of cells that mimic a patient's tumor -- are a promising avenue for drug discovery to improve outcomes in ...