Surgical resection remains the cornerstone of management for chondrosarcoma and chordoma. However, the application of new biologic insights to therapeutic development indicates that improved ...

Regorafenib (Stivarga) did not improve progression-free survival in patients with advanced or metastatic chordoma, according to the noncomparative phase II REGOBONE study, which was presented at the ...

Dr. Jaclyn Biegel, Director, Center for Personalized Medicine, and her colleagues at CHLA found new classes of genetic causes associated with pediatric chordoma, a rare and lethal bone cancer. Little ...

Sacrococcygeal chordoma is rare, with a risk of local relapse of 50%, and metastasis relapse estimated at 17.5% in all cases. 1 Only one metastatic case to the penis has been reported. 2 We report the ...

Nicole Carter has always been a fighter. She enjoys role-playing games where she slays dragons. She’s been known to be stubborn. But, on top of all that, the 26-year-old is in her second battle with ...

Study showed signs of clinical activity, but failed to meet the primary endpoint of the Phase 2 study Two ongoing phase 1 trials are exploring the intravenous administration of two different MVA-based ...

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these ...

During his freshman year at Duke University, a persistent headache sent Josh Sommer on a diagnostic journey. The reveal: a tumor right below his pituitary gland in front of his brainstem. Called a ...

A new study adds to a growing body of evidence that organoids -- lab-grown collections of cells that mimic a patient's tumor -- are a promising avenue for drug discovery to improve outcomes in ...