Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. Davis and co-authors used many mouse models to investigate ...

Using data from Swedish population-based and sibling cohort studies, Yang et al. show that women with premenstrual disorders are at increased risk of cardiovascular disease (CVD). See Yang et al.

Background: Our prior studies suggest that mitral annular septal-lateral (SL) diameter is the chief determinant of “Alfieri stitch” tension, but hemodynamic parameters may also play a role. To study ...

1 Oral and Maxillofacial Surgery Unit, School of Dental Sciences, Universiti Sains Malaysia 2 Department of Oral and Maxillofacial Surgery, Hospital Taiping, Ministry of Health Malaysia Correspondence ...

FIGURE 2. More detailed schematic presentation of histamine synthesis and degradation. Important enzymes involved are mentioned and, additionally, the inhibitors used in this study are shown. AldDH, ...

1 Laboratório de Farmacologia e Neurobiologia, Center for Drug Discovery and Innovative Medicines (MedInUP), Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Porto, Portugal 2 ...

A variety of pathological conditions can increase risk for development of ventricular arrhythmias in humans including diabetes mellitus, obesity, myocardial infarction (MI), and heart failure. Many of ...

Despite these reports and others that have confirmed the presence and importance of this phenomenon in HF, chronotropy remains the “Cinderella” of HF pathophysiology and management: under-appreciated, ...

In response to exercise or other stresses, catecholamines are released into the circulation and within the heart. Catecholaminergic stimulation of β1-adrenergic receptors (β1ARs) in the heart ...

Background— Our prior studies suggest that mitral annular septal-lateral (SL) diameter is the chief determinant of “Alfieri stitch” tension, but hemodynamic parameters may also play a role. We ...