Environmental factors influence human cell physiology and can also affect drug efficacy, but existing model systems used to study human cells have limitations for understanding these contributions. In ...

Membrane depolarization promotes extracellular signal-regulated kinase activation and cell proliferation via phosphatidylserine dynamics.

Eukaryotic cilia and flagella are essential organelles that extend from the cell surface, playing crucial roles in sensory ...

Researchers have mapped variation in human stem cells that explains how cells of an individual may shape a unique 'developmental dance' at the molecular level, thereby controlling how the brain and ...

Spatial and single-cell data from 1.6 million cells have been integrated to create the most comprehensive cell map of the ...

CRISPR-based forward genetic screens can be used to identify essential genes in proliferating human cell lines. Although environmental factors also influence gene essentiality, most CRISPR-based ...

Due to their repetitive and complex DNA sequences, centromeres have been viewed as the "black boxes" of the genome for decades. Often overlooked in sequencing projects but playing a critical role in ...

The physiology program prepares students for a career in original research, teaching, and applied physiology at a college, university, or professional school level. Graduates also find employment in ...