A persistent left-to-right shunt through a patent ductus arteriosus (PDA) increases the rate of hydrostatic fluid filtration into the lung's interstitium (1), impairs pulmonary mechanics (2–7), ...

Closing patent ductus arteriosus (PDA) is a widely accepted approach in the management of very low birth weight (VLBW) infants. Our objective is to test the hypothesis that conservative management (no ...

Philadelphia, PA - Using a strategy that takes the classic "house-call" to new extremes, a traveling medical team made up of cardiothoracic surgeons, anesthesiologists, and nurses is bringing a ...

Of the 350 patients, 165 were treated with indomethacin and 185 received ibuprofen. The 7 cases where both drugs were used were excluded from the analyses of outcomes subsequent to the first course of ...

Active treatment of hemodynamically significant patent ductus arteriosus (PDA) in preterm infants within the first 2 weeks of life was associated with worse outcomes than expectant management.

Patent ductus arteriosus (PDA) is a congenital cardiac defect that occurs when the ductus arteriosus fails to close. The result is a persistent communication between the aorta and pulmonary artery, ...

Please provide your email address to receive an email when new articles are posted on . Compared with surgical ligation, transcatheter closure of the patent ductus arteriosus in infants and neonates ...

The US Food and Drug Administration has cleared the smallest occlusion device to date for the treatment of symptomatic patent ductus arteriosus (PDA) in premature infants, device manufacturer Abbott ...

A patent ductus arteriosus (PDA) is a persistent connection between the aorta and the pulmonary artery resulting in left to right shunting. This connection is supposed to close shortly after birth, ...

“This position statement represents a collective effort between neonatology, anesthesia, and interventional cardiology to provide comprehensive guidance on tcPDA device occlusion that can be adapted ...

SHOULD closure of a patent ductus arteriosus with reversal of flow be attempted? If so, how can the high surgical mortality hitherto reported 1–3 be reduced? An attempt is made to answer these ...

The causes of many sporadic diseases are unexplained; the contribution of recessive loci with reduced penetrance is one possibility that has been difficult to explore. We describe an approach to this ...