WebMD

Dopamine Partial Agonists for Schizophrenia

Among the newer antipsychotic drugs for schizophrenia are a type called dopamine partial agonists. They get this name from the way they work in your brain. You might also hear them called ...
Nature

Crystallizing our understanding of partial agonists

One unresolved issue relates to the mechanism of action of partial agonists. Partial agonists are ligands that can activate the receptor, but not as well as a full agonist. Understanding the actions ...
Business Wire

Synthekine Advances IL-2 Partial Agonist, STK-012, into Clinical Investigation for Treatment of Solid Tumors

MENLO PARK, Calif.--(BUSINESS WIRE)--Synthekine Inc., an engineered cytokine therapeutics company, today announced it is advancing its IL-2 partial agonist, STK-012, into clinical investigation ...
BioWorld

SARs to convert full cannabinoid receptor agonists to partial ones

Activation of cannabinoid receptors in the peripheral nervous system may help treat inflammatory and gastrointestinal disorders as well as pain, and several full agonists have been reported but they ...
Business Wire

Synthekine Doses First Patient in Phase 1 Clinical Trial of IL-2 Partial Agonist, STK-012, for Treatment of Solid Tumors

MENLO PARK, Calif.--(BUSINESS WIRE)--Synthekine Inc., an engineered cytokine therapeutics company, today announced the dosing of the first patient in a Phase 1a/1b clinical trial of its IL-2 partial ...