3-Methyl-6-chloro-7,8-hydroxy-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine (SKF83959) have been shown to affect several types of voltage-dependent channels in hippocampal pyramidal neurons.

"The effects were completely opposite," notes Ohtsuki. The pyramidal cells appeared to react to the same cytokine -- TNFa or tumor necrosis factor alpha -- secreted by activated microglia: one of the ...

The prefrontal cortex (PFC) plays a critical role in curbing impulsive behavior, but the underlying circuit mechanism remains incompletely understood. Here we show that a subset of dorsomedial PFC ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 59, No. 2 (Feb. 15, 1968), pp. 381-384 (4 pages) ...

A new study published in Psychiatry Research provides evidence that certain brain cells are physically smaller in individuals ...