The San Francisco 49ers have signed kicker Matt Gay to their practice squad to replace Eddy Pineiro, and life's been hectic for Gay recently.

The Panthers cannot beat the 49ers. Don’t misconstrue that: The Panthers can win on Monday. They have won six times already this season. But they cannot go toe-to-toe with the 49ers, both teams playing their best, and win. And that makes this game the ultimate litmus test for the Niners.

The San Francisco 49ers' Kyle Shanahan is firmly in the conversation for the Coach of the Year award, an honor for which he's been snubbed twice before. Here's why he may have missed his window.

NFL Week 12 odds, picks, predictions, TV channel, streaming information for Monday Night Football between Carolina Panthers and San Francisco 49ers.

San Francsico 49ers linebacker Curtis Robinson received a major punishment from the NFL from a player in the Week 11 win.

Jason Pinnock was benched after Week 5, but he has played 80 snaps in the 49ers' dime look since then. However, he has not been good in that role. Pinnock allowed five catches, including a touchdown, in his expanded role against the Arizona Cardinals. That should signal a time to switch things up, as he was one of the few issues in that game.

Find single game tickets to the San Francisco 49ers vs. Carolina Panthers NFL Week 12 matchup on Monday, November 24, 2025 at Levi's Stadium.

Among the decisions the San Francisco 49ers will have to make throughout the offseason, it sounds like trading Mac Jones is a possibility.

The San Francisco 49ers have a big game against the Carolina Panthers that will swing the playoff odds in a big way, depending on who wins. San Francisco is favored, mostly because the Panthers' passing game is limited. If the 49ers want to win, they essentially just have to shut down one player.