Everyone knows that scratching relieves an itch–but how? Neuroscientists now say they’ve found part of the answer in a new study of macaque monkeys. Previous research has suggested that a specific ...
Pain and itch are distinct sensations arousing evasion and compulsive desire for scratching, respectively. It’s unclear whether they could invoke different neural networks in the brain. Here, we use ...
Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch
We found a class of lamina I spinothalamic tract (STT) neurons selectively excited by iontophoretic histamine. The responses of this class of neurons parallel the pure itching sensation this stimulus ...
ALTHOUGH our Puritan ancestors may have thought that pain was a scourge of God to try the soul of man, few modern philosophers would agree with this concept. The attempt to control chronic pain by ...
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