Guardians update (54-54): They’ve won 14 of their last 20 games. Carlos Santana .400 (6 for 15) with two homers and two RBI and Jose Ramirez .320 (8 for 25) have hit the Twins well this year. Williams, who opens the series against the Twins, is 1-1 against them this year.

Pregame analysis and predictions of the Minnesota Twins vs. Cleveland Guardians MLB game to be played on August 1, 2025 on ESPN.

A look ahead to the MLB game between TWINS and GUARDIANS. Your source for scores, previews, recaps, box scores, and more from every Major League Baseball. The schedule is set, and we're ready for some baseball.