Colts’ Jonathan Taylor; Ricky Pearsall Jr. doesn’t practice but Kyle Shanahan likes his chances to play Monday.

The 49ers and Colts meet for a Monday Night Showdown. Check our NFL odds series for the 49ers-Colts prediction and pick.

The 49ers aren't taking Philip Rivers lightly as the veteran QB returns with the Colts, setting up a high-stakes Monday night ...

San Francisco 49ers coach Kyle Shanahan and running back Christian McCaffrey share their impressions of Indianapolis Colts ...

San Francisco 49ers TE George Kittle, RB Christian McCaffrey, and DL Keion White discussed the energy inside the locker room, ...

San Francisco 49ers head coach Kyle Shanahan highlighted Indianapolis' run defense, reflected on overcoming injuries, and ...

McCaffrey ranks third in the league in total scrimmage yards with 1,742. The only players he's behind are Bijan Robinson and ...

Let’s keep the streak going. We have found some success with our NFC West Bold Predictions, but now the heat is on. The Los ...

Lucas Oil Stadium is the location where the Indianapolis Colts (8-6) will meet the San Francisco 49ers (10-4) on Monday.

Tampa Bay and Carolina will meet in Charlotte with first place in the NFC South on the line on Sunday, and the visitors will ...

Monday, 8:15 p.m. EST, ESPN. BetMGM NFL odds: 49ers by 6. Against the spread: 49ers 9-5; Colts 8-6. Series record: Colts lead 27-18. Last meeting: Colts ...

Cam Skattebo went down in Week 8. Weeks 9 and 10 were an adjustment, but since Week 11, Tracey is the RB12 in PPG, delivering ...