The NFC West is loaded at the top, and two of the division's contenders meet on Sunday when the 6-3 San Francisco 49ers host the 6-2 Los Angeles Rams. This is the second meeting between these two rivals, as the 49ers won the Week 5 matchup 26-23 in overtime on Thursday Night Football.

In Sunday's showdown at Levi's Stadium, the Rams looked like they were on their way to a big win after jumping out to a 21-0 lead thanks to touchdowns on their first three drives, but the 49ers stuck around. They scored 14 straight points to make it a one-possession game just after halftime, finding a rhythm on offense with Mac Jones airing it out.

The Los Angeles Rams are in Santa Clara today for their second meeting with the San Francisco 49ers, a rematch of their Week 5 showdown. The Rams are seeking their fourth straight victory since that loss to the 49ers, playing like one of the best teams in the league.

The San Francisco 49ers are looking to string two wins together for the first time since starting 3-0 as they host the Los Angeles Rams in Week 10.  It’ll be a

The San Francisco 49ers dropped to 6-4 on the season after a 42-26 Week 10 loss to the Los Angeles Rams at Levi's Stadium in Santa Clara, California. Below are several statistics and notes from Sunday's game,

Highlights from the Week 10 matchup between the Los Angeles Rams and the San Francisco 49ers during the 2025 NFL season.

Two of the NFC’s most proven contenders take the field Sunday in Santa Clara, Calif., where the San Francisco 49ers host a pivotal West Division clash with the Los Angeles Rams.

The San Francisco 49ers host the Los Angeles Rams in a huge NFC West matchups. Here's the start time and where to watch.

Tampa Bay dominated New Orleans 23-3 in their last game, before last week's bye. Baker Mayfield is having an MVP-caliber first half of the season, passing for 1,919 yards, 12 touchdowns and 2 interceptions. Follow along here for live updates on Patriots-Bucs and the rest of the games in the early and afternoon matchups.