Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside ...

In their new study, the LJI scientists are the first to show that GPR25 is induced by a signaling molecule called TGF-β.

Chemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic ...

UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors ...

New research, led by LJI scientists, offers a potential way to boost tissue-resident memory T cell numbers to better fight disease.

New research reveals that neurons release a little-understood extracellular kinase called VLK to strengthen synaptic ...

Two research teams 3000 miles apart discover a common bacterium triggering chronic gastrointestinal pain — while developing a ...

A class of synthetic drugs called nitazines have been around since the 1950s — but are quickly gaining a foothold in street drugs.

But the scientists also discovered that inhibiting the TAS2R receptors made the cells more receptive to the drug's effects. They propose that in further research, the role the bitter taste receptors ...

Once a drug target is identified, it often takes decades until a chemical compound is developed that can hit the bullseye and ...

ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. ProPublica wanted to know something simple: Where a widely ...