Tectonic Therapeutic, Inc. (NASDAQ: TECX) (“Tectonic”), a clinical stage biotechnology company focused on the discovery and development of therapeutic proteins and antibodies that modulate the ...
This important study fills a gap in our knowledge of the evolution of GPCRs in holozoans, as well as the phylogeny of associated signaling pathway components such as G proteins, GRKs, and RIC8 ...
This article and associated images are based on a poster originally authored by Sam Hoare, Luciana Leo, Anastasia Schultz, and Thom Hughes and presented at ELRIG Drug Discovery 2025 in affiliation ...
Orexin receptors (OXRs), including OX1R (HCRTR1) and OX2R (HCRTR2), are G protein-coupled receptors (GPCRs) that are activated by endogenous orexin peptides (OXA and OXB) and have potential ...
Tyler Fritsch is a 2 nd year student in the Microbiology, Immunology, and Infectious Disease training group where he works in Dr. Matosevic’s Lab in the IMPH Department. The Matosevic lab primarily ...
Background: Human Relaxin-2 (RLN2) signals via G-protein coupled receptor (GPCR) relaxin family peptide receptor 1 (RXFP1), and exerts vasodilatory, anti-inflammatory, and anti-fibrotic effects in the ...
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