Aluminum's journey has been remarkable, going from being more expensive than gold to one of the most widely used materials, ...

a. Schematic diagram of aggregate structure in NaCl crystal. b. Schematic diagram of chemical structure in zwitterionic aggregate. c. Visualization of the inter- and intramolecular motion in ...

Major Finding: Intramolecular bivalent glues simultaneously engage two separate sites in cis on a target protein to induce degradation. Concept: A conformational change is induced upon cis protein ...

Living cells resemble highly organized small towns - in addition to energy production, transportation systems, and construction, cells also require efficient waste disposal. Most proteins, which shape ...

Research led by the Centre for Targeted Protein Degradation (CeTPD) in the University of Dundee identified a breakthrough class of molecular glue that could pave the way for a new generation of drugs ...

A breakthrough class of molecular glue identified at the University of Dundee could pave the way for a new generation of drugs to target cancers and neurodegenerative diseases. A research team at the ...

Frumkin Institute of Physical Chemistry and Electrochemistry Russian Academy of Sciences, 31 Bldg 4, Leninsky Prosp., Moscow 119071, Russian Federation Article Views are the COUNTER-compliant sum of ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Phase-transfer-catalyzed intramolecular cyclization reaction of forming benzo[b]furan and 3-methyleneisoin- doline-1-one derivatives has been developed. The cyclization reaction of propargylic ...