Introduction: Myopathy, encephalopathy, lactic acidosis, and stroke-like (MELAS) syndrome, a maternally inherited disorder that is among the most common mitochondrial DNA (mtDNA) diseases, is usually ...

A Thai hospital’s new fast-track dialysis protocol cut deaths from a rare metformin complication nearly in half. The study ...

Health care professionals can have a powerful impact on labeling requirements for drugs by formally petitioning the FDA for ...

SEVERE metabolic acidosis, when it occurs in diabetic patients, is generally the result of excessive hepatic production of acetoacetic and beta-hydroxybutyric acid. Exceptional cases of metabolic ...

Metformin (1,1-dimethylbiguanide hydrochloride), is today, the most prescribed oral medicine for type 2 diabetes, taken by millions of people every day. It is inexpensive, effective, and widely ...

A Conestoga man is facing involuntary manslaughter and neglect related charged after a woman he was allegedly caring for passed away in September 2024. According to an affidavit, on September 6, 2024, ...

What began as a mother’s attempt to capture a picture-perfect vacation moment aboard Disney Cruise Line’s Disney Dream ended in tragedy, as police say a 5-year-old girl plunged from a deck after being ...

Mother will not face charges after daughter falls from Disney cruise ship The Broward State Attorney’s Office has declined to charge a mother with child neglect after her daughter fell from a Disney ...

It was once believed that lactic acid buildup in the muscles was the cause of soreness and fatigue following a strenuous workout. However, recent research indicates that this is due to inflammation ...

As if growing up in one of Chicago’s most dangerous neighborhoods wasn’t hard enough, Darryl Hall was born with a rare condition that caused a foul odor to ooze from his pores as a teenager. “I was ...

Metformin is often the first medicine you’ll take if you have type 2 diabetes—for many reasons. It helps bring down your blood sugar level in three ways: It tells your liver to make less glucose. It ...

The pyruvate dehydrogenase complex (PDHc) plays a key role in metabolism by linking glycolysis to the tricarboxylic acid cycle and converting pyruvate into acetyl-CoA. However, due to its large size ...