The group of researchers were the first to take snapshots of the moment naloxone reverses an opioid overdose in the brain.

Scientists have visualized for the first time how opioids such as loperamide and the antidote naloxone engage a key brain receptor, offering insight that could lead to better pain treatments.

Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

Having a pill that alleviates chronic pain without adverse side effects or the risk of addiction remains an unmet pharmaceutical need for millions of people currently using traditional opioid drugs.

Opioid antagonists are medications people can take to treat opioid use disorder. They help by reducing withdrawal symptoms, addressing cravings, and managing overdoses. Doctors prescribe opioid ...

By Dennis Thompson HealthDay ReporterTHURSDAY, Nov. 20, 2025 (HealthDay News) — The opioid addiction medication buprenorphine ...

A class of synthetic drugs called nitazines have been around since the 1950s — but are quickly gaining a foothold in street drugs.

The United States recently hit a grim milestone: More than 100,000 Americans died from drug overdoses between May 2020 and April 2021. The majority of those deaths were due to synthetic opioids, which ...

BOSTON (StudyFinds.org) – Redheads have a reputation for being hot-tempered. They also are said to have a higher pain threshold than others. Although there may not be scientific proof of their short ...