By William J. Broad In 1999, William J. Broad and two colleagues wrote a comprehensive article on the past, present and future of the smallpox virus. Feb. 12, 2025 President Trump’s order that ...

Smallpox, a disease that killed an estimated 500 million people in the 20th century alone, is the only human disease to be eradicated. However, a new report, "Future State of Smallpox Medical ...

Unlike smallpox and human monkeypox diseases ... This review highlights recent advances made in the field of MCV pathogenesis, and the clinical and biological implications of these findings ...

Since smallpox vaccines in development cannot be tested for clinical efficacy, the Animal Rule will most likely be used to evaluate the efficacy of new-generation smallpox vaccines, per 21 CFR 601.90.