Sam Tighe has a look at the best betting markets for this Wednesday’s Champions League knockout second-leg clashes.

When the final whistle blows at the Bernabeu on Wednesday night there will be at least two certainties facing the revamped Uefa Champions League. Firstly, either reigning champions Real Madrid or the 2023 victors Manchester City will be absent from the last-16 draw that takes place on Friday in Switzerland.

Making light of Real Madrid's furious Ballon d'Or snub when Los Blancos learned that Rodri would pip Vinicius Junior to the top prize, Man City fans unfurled a banner of their Spanish metronome kissing the accolade with the tagline "Stop crying your heart out" - an ode to Citizens-crazed Oasis - last week.

Follow live text commentary, score updates and match stats from Manchester City vs Real Madrid in the UEFA Champions League

While Real are top of LaLiga having lost just three times all season, City are fourth in the Premier League, 16 points behind the leaders Liverpool having lost seven games which is four more than they lost in the whole of last season.

Manchester City and Real Madrid meeting in the Champions League has become synonymous with the competition. While both always have ambitions of winning the entire thing, these two teams have already met 12 times in Champions League play with five of those meetings coming in the knockout stage.

Previous meetings, form guides, links and trivia ahead of the UEFA Champions League knockout phase play-off first leg.

Pep Guardiola believes Manchester City only have a "one percent" chance of keeping their Champions League dreams alive when they face Real Madrid in the second leg of their playoff round on Wednesday in Spain.

Real Madrid has long been considered to be the biggest club in world football, and their incredible success in the Champions League has played a large part in t