Can San Francisco's offense ignite against a vulnerable Cardinals defense? Find out if the 49ers can rebound after last ...

It wasn't an easy outing for the San Francisco 49ers in the initial matchup with the Arizona Cardinals. Their rematch with ...

Injuries and veteran leadership clash as key defenders aim to dominate this crucial NFC West showdown. Keep your eyes on ...

San Francisco 49ers running back Christian McCaffery catches a short pass from quarterback Mac Jones for a 19-yard gain.

Seattle Seahawks linebacker Boye Mafe drops Arizona Cardinals quarterback Jacoby Brissett for a 15-yard sack which forces ...

www.si.com/nfl/cardinals/onsi Star Cardinals Pass Rusher Suddenly Missing From Practice ...

Seahawks and Rams battle for NFC West supremacy. 49ers chase, Cardinals scrap, setting up a thrilling divisional showdown.

The San Francisco 49ers have a very unexpected quarterback controversy brewing in the Bay, as Mac Jones has filled in more ...

Quarterback Brock Purdy returns to the starting lineup for the San Francisco 49ers this week after missing six games with a ...

The San Francisco 49ers receive a candid message on Brock Purdy and Mac Jones as the quarterback situation draws attention.

Mac Jones opened up about his decision to sign with the 49ers in free agency after the team's Week 10 loss to the LA Rams.

San Francisco 49ers head coach Kyle Shanahan announced the team's starting quarterback for Week 10's matchup against the Rams ...