Primary lateral sclerosis (PLS) and amyotrophic lateral sclerosis (ALS) are neurodegenerative diseases. PLS typically develops slowly, while ALS rapidly affects mobility and can become fatal.

When you take a walk, talk to a friend, or chew a piece of food, motor neurons are behind these movements. Just like other parts of your body, they can become damaged. You may have heard of ALS, ...

A diagnosis of amyotrophic lateral sclerosis can be overlooked by clinicians unfamiliar with the various signs of the disease. ALS is purely a motor neuron disease; sensory neurons are not affected. 4 ...

Areflexic, or flaccid, bladder and bowels occur when the spinal cord injury is low enough to damage the cauda equina and alpha motor neurons. It also occurs in all spinal cord injury patients during ...

SBT-272 improved neuronal health, superior to other approved and investigational agents Phase 1 study to evaluate safety and tolerability of SBT-272 in healthy volunteers is underway BOSTON, June 8, ...

Current clinical assessments evaluating selective voluntary motor control are measured on an ordinal scale. We combined the Selective Control of the Upper Extremity Scale (SCUES) with surface ...

Primary lateral sclerosis (PLS) is a rare neurological disorder that affects the motor neurons in the brain and spinal cord, which control movement. It is a form of motor neuron disease (MND). PLS ...

Progressive muscular atrophy (PMA) is a rare adult-onset motor neuron disease. Although there’s no cure, treatments may slow down nerve damage and reduce symptoms. Progressive muscular atrophy (PMA) ...