The brain damage seen in encephalitis lethargica can sometimes leave patients in a statue-like state. A worldwide epidemic of the condition occurred between 1915 and 1925 and although no further ...

The cause of encephalitis lethargica is unknown. An epidemic of encephalitis lethargica (between 1917 to 1928) hit the world, but there hasn’t been any case of recurrence ever since. Symptoms ...

But the 20th-century epidemic of encephalitis lethargica started in 1915, before the influenza pandemic, and continued into the 1930s, so a direct link between the two has remained difficult to prove.

Damage to this region is thought to occur in encephalitis lethargica. Lutters et al. explain how the outbreak also advanced our understanding of Parkinson’s disease. Post-mortem studies of the brains ...

But the 20th-century epidemic of encephalitis lethargica started in 1915, ... One, of course, is that we may see widespread brain damage following this viral pandemic.

An epidemic of 'brain damage linked to the pandemic' ... Between 1917 and the 1930s, more than 1 million people were diagnosed with encephalitis lethargica, or "the sleepy sickness." ...

"Whether we will see an epidemic on a large scale of brain damage linked to the pandemic – perhaps similar to the encephalitis lethargica outbreak in the 1920s and 1930s after the 1918 influenza ...

The role, either direct or indirect, of the influenza virus in encephalitis lethargica is still up for debate, but scientists have linked other respiratory viruses, like SARS-CoV-2, to ...

The cause of encephalitis lethargica remains one of the largest medical mysteries of the 20th century, though some scientists contend that the Spanish Flu may have been the trigger.

For instance, encephalitis lethargica and post-encephalitic parkinsonism emerged following the Spanish flu (influenza A H1N1) pandemic a hundred years ago. ... causing hypoxic brain damage.