Sensetics, a next generation haptics and touch data company advancing the digital capture and transmission of realistic touch experiences and bridging the machine and physical worlds by bringing touch ...

Piezo2 is increased in idiopathic pulmonary fibrosis (IPF). Immunohistochemistry of nonfibrotic (left) and IPF (right) lung tissue demonstrating that Piezo2 (brown staining) is strongly present in ...

Low-threshold mechanoreceptors (LTMRs) and their cutaneous end organs convert light mechanical forces acting on the skin into electrical signals that propagate to the central nervous system. In mouse ...

A novel vibrating capsule that signals a postprandial feeling of fullness reduced both food and energy intake and lowered weight gain in animal studies, said researchers who are developing it as a ...

Introduction: About 500,000 people worldwide die annually from ruptured intracranial aneurysms (IA). The pathophysiology of aneurysm formation is largely unknown. Piezo1 mechanoreceptors are expressed ...

Touch perception begins with activation of functionally distinct classes of primary mechanosensory neurons, called low-threshold mechanoreceptors (LTMRs), and propagation of their signals to the ...

The encoding of touch in the spinal cord dorsal horn (DH) and its influence on tactile representations in the brain are poorly understood. Using a range of mechanical stimuli applied to the skin, ...

Department of Electrical and Computer Engineering, Wayne State University, Detroit, 48202, United States Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 ...

Our editorial process produces two outputs: (i) public reviews designed to be posted alongside the preprint for the benefit of readers; (ii) feedback on the manuscript for the authors, including ...

Acupuncture is an effective alternative therapy for pain management. Evidence suggests that acupuncture relieves pain by exciting somatic afferent nerve fibers. However, the mechanism underlying the ...

Embryonic development relies on a hierarchy of transcription factor expression and chromatin structure changes to establish unique patterns of gene expression in different cell types. The mechanisms ...