People for the Ethical Treatment of Animals, known for controversial tactics to draw attention to animal welfare, will drive its “Hell on Wheels” truck through the Upstate this weekend.

Strong storms are heading to the Upstate, the National Weather Service says, and tornadoes could spin out of them.

A severe weather/tornado outbreak threatens our area Saturday night with a now higher risk for potentially strong tornadoes.

The impending execution of an Upstate man on South Carolina’s death row has been put on pause. The Supreme Court of South ...

FOX Carolina Investigates now has 80 pages of incident reports from the Greenville County Sheriff’s Office that outline what led up to Lionel’s escape and the law enforcement search that followed.

The McClaren Institute for Health & Quality of Life, headquartered in Downtown Greenville, will provide wellness programs, ...

Deputies in Oconee County, South Carolina, arrested a Georgia man on a drug trafficking charge after deputies discovered more ...

Doctors at Prisma Health said South Carolina could see cases of the measles with expected travel over spring break.

One of the four men U.S. Rep. Nancy Mace accused of being a sexual predator is now suing her for defamation, claiming that ...

Georgia's weekend series against a ranked South Carolina team will be streamed through the SEC Network+. Fans looking to ...

Parts of South Carolina face strong storms that could produce damaging winds, tornadoes and some flooding this weekend.