DNA mismatch repair (MMR) is a system for recognizing and repairing erroneous insertion, deletion, and mis-incorporation of bases that can arise during DNA replication and recombination, as well as …

DNA mismatch repair (MMR) is defined as the process that corrects errors introduced during DNA replication by replacing mismatched nucleotides and repairing insertion/deletion loops.

Apr 29, 2025 · This article explores the processes of DNA mismatch repair, highlighting key types of mismatches, the enzymes responsible for correction, and how these systems function differently …

DNA mismatch repair (MMR) maintains genomic stability primarily by correcting replication errors. Defects in MMR lead to cancers and cause resistance to many chemotherapeutic drugs.

Dec 24, 2007 · DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. The specificity of MMR is primarily for base-base mismatches …

Aug 3, 2025 · Once a mismatch is found, the repair complex identifies the newly synthesized strand by detecting nicks or specific markers. It then removes a segment of the strand containing the mismatch …

DNA mismatch repair refers to the rescue system that conserves the DNA sequences by removing the erroneous mismatched, inserted or deleted bases during the DNA duplication and recombination.

Jan 1, 2018 · DNA mismatch repair (MMR) is the process by which misincorporation errors during semiconservative replicative DNA synthesis are corrected. To correctly repair such DNA mispairs, …

Oct 23, 2024 · This review provides an overview of how these paradigms have been used to explain DNA mismatch repair, which involves several steps that require action-at-a-distance. Here, we …

DNA mismatch repair (MMR) proteins are essential for the recognition and correction of sporadic genetic mutations that occur during DNA replication. Deficient MMR function (dMMR) leads to an increased …