After the histone translation, its amino tail undergoes various modifications, such as methylation, acetylation, phosphorylation, ubiquitination, malonylation, propionylation, butyrylation, crotonylation, …

Histone proteins undergo post-translational modification (PTM) in different ways, which impacts their interactions with DNA. Some modifications disrupt histone-DNA interactions, causing nucleosomes …

Mar 22, 2025 · Histone modification is one of the core mechanisms of epigenetics, which affects the structure of chromatin and the expression of genes by changing the intensity of interaction between …

Histone modification refers to post-translational modifications of histone proteins, primarily occurring on their N-terminal tails, including acetylation, methylation, phosphorylation, ubiquitination, and …

Feb 15, 2011 · Chromatin is not an inert structure, but rather an instructive DNA scaffold that can respond to external cues to regulate the many uses of DNA. A principle component of chromatin that …

Oct 13, 2025 · Histones can be modified through several chemical processes, including acetylation, methylation, phosphorylation, and ubiquitination. Each modification either loosens or tightens DNA …

Aug 8, 2025 · Histone modification refers to posttranslational alterations on histone proteins, typically through the addition or removal of chemical groups or small protein modifiers at specific amino acid …

In this compact form, transcriptional machinery cannot access DNA, resulting in gene silencing. In this way, modification of histones by chromatin remodeling complexes changes chromatin architecture …

A histone modification is a covalent post-translational modification (PTM) to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation.

Histones are the principal protein component of chromatin and their post-translational modifications play important roles in regulating the structure and function of chromatin and thereby in determining cell …