MTHFR Gene Variant and Folic Acid Facts | Folic Acid | CDC
May 27, 2025 · You may have heard that if you have an MTHFR variant, you should avoid folic acid and should take other types of folate, such as 5-MTHF. However, this is not true.
Methylenetetrahydrofolate reductase - Wikipedia
Methylenetetrahydrofolate reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. [5] Methylenetetrahydrofolate reductase catalyzes the conversion of …
MTHFR Gene Mutations: What You Need to Know - WebMD
MTHFR gene mutation affects folate metabolism, linked to higher risk of cardiovascular issues, blood clots, and certain birth defects. It influences methylation and homocysteine levels.
MTHFR mutation: Symptoms, testing, and treatment
Aug 21, 2025 · Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that breaks down the amino acid homocysteine. If the MTHFR gene that codes for this enzyme mutates, it may contribute to …
MTHFR Gene Mutation: Deficiency, Symptoms, Testing, Treatments
Sep 9, 2024 · Read on to learn more about the MTHFR gene mutation symptoms, testing, and treatments. MTHFR gene mutations can cause elevation of blood homocysteine levels, some of …
MTHFR is a gene that makes an enzyme called MethyleneTetraHydroFolate Reductase. This enzyme works with a B-vitamin called folate. Together, MTHFR and folate help to reduce the level of …
MTHFR Gene Mutations and Disease - Verywell Health
Nov 10, 2025 · Methylenetetrahydrofolate reductase (MTHFR) is an enzyme produced by the MTHFR gene. MTHFR interacts with folate (vitamin B9) to break down homocysteine so that it can be …
MTHFR Gene: Key Facts, Symptoms, and Treatment Options
The MTHFR gene is essential for processing folate in the body. Mutations in this gene can lead to elevated homocysteine levels, which are linked to various health issues, including cardiovascular …
What is methylene tetrahydrofolate reductase (MTHFR)? MTHFR is a gene, not a disease or genetic condition. The MTHFR gene serves many functions. One of its most important functions is providing …
MTHFR: The Complete Guide to Understanding & Managing MTHFR
Think of MTHFR as a crucial factory worker in your body’s cellular machinery. Its main job is to convert folate (vitamin B9) from your diet into its active form called methylfolate.