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  1. About Sickle Cell Disease | Sickle Cell Disease (SCD) | CDC

    Feb 21, 2025 · Sickle cell disease (SCD) is a group of inherited blood disorders. Abnormal hemoglobin is produced. Red blood cells become hard and sticky and get stuck in small blood vessels, resulting …

  2. Sickle Cell Disease (SCD) Symptoms, Causes & Types

    Sickle cell disease (SCD) is an inherited blood disorder. It causes your red blood cells to form into a “C” shape. It can cause pain and serious complications.

  3. Sickle Cell Disease - What Is Sickle Cell Disease? | NHLBI, NIH

    Dec 10, 2025 · Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells. Normally, red blood …

  4. Sickle Cell Disease (SCD): Symptoms, Causes, and Treatment

    Sep 28, 2025 · Sickle cell disease (SCD) is an inherited blood disorder that affects red blood cells. Common symptoms include anemia, fatigue, severe pain, and swelling.

  5. Sickle cell anemia - Symptoms & causes - Mayo Clinic

    Sep 12, 2025 · Sickle cell anemia is one of a group of inherited disorders known as sickle cell disease. It affects the shape of red blood cells, which carry oxygen to all parts of the body. Red blood cells are …

  6. Sickle Cell Disease | Sickle Cell Anemia | MedlinePlus

    Sep 6, 2024 · What causes sickle cell disease (SCD)? SCD is caused by a variant (change) in a gene that has instructions for your body to make one part of the hemoglobin. This changed gene is …

  7. Sickle Cell Disease - Johns Hopkins Medicine

    What is sickle cell disease? Sickle cell disease (SCD) is an inherited blood disorder. That means it is passed down from a parent’s genes. It causes the body to make abnormal hemoglobin. Hemoglobin …

  8. What Is Sickle Cell Disease? Sickle cell disease (SCD) is a group of inherited red blood cell disorders. • Healthy red blood cells are round and they move through small blood vessels carrying oxygen to all …

  9. Sickle Cell Disease (Sickle Cell Anemia) - Causes & Types - WebMD

    Nov 19, 2024 · Sickle cell disease (SCD) is the most common inherited blood disorder. That means it’s passed down through families. You’re born with SCD. It’s not something you catch or develop later in …

  10. Sickle-cell disease - World Health Organization (WHO)

    Aug 6, 2025 · Sickle-cell disease (SCD) is a genetic disorder that affects haemoglobin, the molecule in red blood cells responsible for carrying oxygen. The disease causes red blood cells to become rigid …