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  1. Rofecoxib - Wikipedia

    Rofecoxib is a COX-2-selective nonsteroidal anti-inflammatory drug (NSAID). It was marketed by Merck & Co. to treat osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, acute pain conditions, …

  2. Vioxx: Side Effects, Dosage & Uses - Drugs.com

    Feb 14, 2025 · Vioxx is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Vioxx works by reducing substances that cause inflammation, pain, and fever in the body.

  3. Vioxx | Treatment for Arthritis & Recall for Patient Deaths

    Dec 23, 2025 · Vioxx was once a popular drug to treat arthritis. But manufacturer Merck & Co. pulled it from the market in 2004 amid safety concerns. Research linked the drug to thousands of fatal heart …

  4. Vioxx (rofecoxib) Questions and Answers | FDA

    Merck announced a voluntary worldwide withdrawal of Vioxx (rofecoxib). 2. What is Vioxx? Vioxx is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). Vioxx is also related to the...

  5. Timeline: The Rise and Fall of Vioxx - NPR

    Nov 10, 2007 · Shortly before the FDA approved Vioxx in 1999, drug maker Merck launched a study it hoped would prove that Vioxx was superior to older painkillers, because it caused fewer …

  6. Vioxx News -- ScienceDaily

    6 days ago · Read the latest medical and scientific information on Vioxx and the link between certain medications and heart attacks.

  7. SEPTEMBER 30, 2004, Merck & Co. withdrew its blockbuster arthritis med-ication rofecoxib (Vioxx) from the market after the drug was found to increase the risk of myocardial infarction (MI) and stroke.

  8. The story of Merck’s COX-2 inhibitor, Vioxx (rofecoxib)

    By selectively inhibiting COX-2, Vioxx promised effective pain relief for conditions like arthritis, while minimizing gastrointestinal damage. Approved by the FDA in 1999, Vioxx quickly became a …

  9. Vioxx (Rofecoxib): Side Effects, Uses, Dosage, Interactions ...

    Aug 17, 2022 · Vioxx (rofecoxib) is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis and certain forms of juvenile …

  10. rofecoxib (Vioxx): Drug Facts, Side Effects and Dosing

    Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain, particularly the pain of osteoarthritis and menstrual cramps. Prostaglandins are chemicals that are important in …