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1:22
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This is what a wheeze sounds like In asthma, JRCALC describes 3 causes of narrowing. 1️⃣ Swelling of the bronchial mucosa. 2️⃣ Bronchospasm, where the bronchial smooth muscle contracts. 3️⃣ Increased mucus and secretions. 🫨 As air passes through the narrowed airway, the airway walls vibrate. That vibration is what is heard on auscultation. Breathing in is an active process, and the respiratory muscles overcome the narrowing. Breathing out relies on muscle relaxation, so airflow slows through th
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Administering low-dose intravenous ketamine transforms multimodal general anesthesia by targeting central pain pathways before surgical stimulation begins. Ketamine functions as a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, dampening dorsal horn wind-up and preventing acute central sensitization (Peltoniemi et al., 2016). When combined synergistically with gamma-aminobutyric acid (GABA) receptor agonists like propofol, it produces reliable hypnotic depth and somatic analgesia
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